Hematology
HEME · guidelines, resources & primary literature
Guidelines & Resources
General
- Thrombosis Canada Clinical Guides — Thrombosis Canada
- Oral Antithrombotic Agents Overview — RxFiles
- Warfarin Dosing Nomogram — RxFiles
VTE
- Thrombosis Canada Clinical Guides — Thrombosis Canada
- Pulmonary Vascular Guidelines — CHEST 2021
- Perioperative Anti-thrombotic Management — RxFiles
Anemia
- Iron Preparations and OTC Products — RxFiles
- IDA Guidelines — BC Guidelines 2023
Anemia of CKD
- CKD Non-Dialysis Anemia — BC Renal 2021
- CKD HD Anemia — BC Renal 2021
- CKD PD Anemia — BC Renal 2021
- SFLC Ratio in CKD — (*eg. How to adjust SFLC ratio in the context of CKD*)
Primary Literature
VTE
DVT / PE Treatment
- EINSTEIN-PE — Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary Embolism — NEJM 2012
- AMPLIFY — Oral Apixaban for the Treatment of Acute Venous Thromboembolism — NEJM 2013
- HOKUSAI-VTE — Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism — NEJM 2013
- COBRRA — Bleeding Risk with Apixaban vs. Rivaroxaban in Acute Venous Thromboembolism — NEJM 2026
Extended Anticoagulation
- AMPLIFY-EXT — Apixaban for Extended Treatment of Venous Thromboembolism — NEJM 2013
- EINSTEIN CHOICE — Reduced-Dose Rivaroxaban in the Long-Term Prevention of Recurrent Symptomatic Venous Thromboembolism — NEJM 2017
Subsegmental PE / Provoked VTE
- PEITHO — Fibrinolysis for Patients with Intermediate-Risk Pulmonary Embolism — NEJM 2014
- PE-TRACT — Anticoagulation for Subsegmental Pulmonary Embolism — NEJM 2024
Cancer-Associated Thrombosis
- CLOT — Low-Molecular-Weight Heparin versus a Coumarin for the Prevention of Recurrent Venous Thromboembolism in Patients with Cancer — NEJM 2003
- CARAVAGGIO — Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer — NEJM 2020
Anemia / Iron Deficiency
Transfusion Thresholds
- TRICC — A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care — NEJM 1999
- FOCUS — Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery — NEJM 2011
- TRISS — Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock — NEJM 2014
IV Iron
- IRONMAN — Intravenous Ferric Derisomaltose in Patients with Heart Failure and Iron Deficiency — Lancet 2022
- FAIR-HF2 — Ferric Carboxymaltose in Heart Failure with Iron Deficiency — Lancet 2024
Anemia of CKD
Thrombocytopenia
ITP
- Romiplostim for ITP — Romiplostim or Standard of Care in Patients with Immune Thrombocytopenia — NEJM 2008
- Eltrombopag for ITP — Eltrombopag for Management of Chronic Immune Thrombocytopenia — NEJM 2008
HIT
- Argatroban for HIT — Treatment and Prevention of Heparin-Induced Thrombocytopenia — Blood 1996