Evidence-Based Medicine

EBM · guidelines, resources & primary literature

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Databases

Appraise

Tools

Users' Guides

How to Use a Noninferiority Trial — JAMA 2012
How to Read a Systematic Review and Meta-Analysis and Apply the Results to Patient Care — JAMA 2014

Outcomes & Stats

Resources

Reading

Making Sense of Statistics in Clinical Trial Reports — JACC 2015 (Part 1 of 4)
Statistical Controversies in Reporting of Clinical Trials — JACC 2015 (Part 2 of 4)
Design of Major Randomized Trials — JACC 2015 (Part 3 of 4)
Challenging Issues in Clinical Trial Design — JACC 2015 (Part 4 of 4)
Nonproportional Hazards for Time-to-Event Outcomes in Clinical Trials — JACC 2019
Win Ratio Method for Hierarchical Composite Outcomes in Randomized Clinical Trials — JAMA 2026